As we approach 2025, the world of aesthetic medicine is shifting from simple surface-level treatments to deep, cellular rejuvenation. At Glory Aesthetics, we believe in staying ahead of the curve. The new wave of skin care isn’t just about what you put on your face—it’s about how you fuel your cells, manage stress, and balance your hormones.

Here is your ultimate guide to the trending molecules and holistic therapies that are set to redefine beauty and wellness in 2025.

1. NAD & NMN: The “Energy Boosters” for Anti-Aging

One of the most talked-about trends for 2025 is NAD (Nicotinamide Adenine Dinucleotide).

What is it? NAD is a critical coenzyme found naturally in every living cell of your body. It is involved in a myriad of metabolic processes and is widely known as a master “energy booster”.

The Problem: As we age, our natural NAD levels decrease, leading to cellular decline [1].

The Benefits: Restoring NAD levels is essential for:

• Cellular Repair: It repairs damaged DNA and increases cellular production.
• Anti-Aging: It slows down the aging process and cellular decline [2].
• Whole-Body Wellness: It improves metabolism, detoxifies the body, reduces stress, and enhances mood.
• Mental Performance: Patients report better energy support and improved mental clarity.

How to Take It: While NAD is available in tablet form, these often lack good absorption. At Glory Aesthetics, we recommend:

• NAD+ IV Drips: Delivers the molecule directly into the bloodstream for maximum efficacy.
• NMN (Nicotinamide Mononucleotide): If you prefer oral supplements, NMN is preferred over NAD tablets. It absorbs quickly, has antioxidant benefits, and converts into NAD within the body to recover depleted levels [3].

2. Malassezin: The “Next Generation” Vitamin C

Move over, Vitamin C. There is a new powerhouse in town called Malassezin.

Derived as a natural compound from the Malassezia yeast, this molecule [4] is making waves for its ability to outperform traditional brightening agents without irritation.

Why We Love It:

• Superior to Vitamin C: It offers more benefits than Vitamin C with virtually no side effects [5].
• Barrier Repair: It is fantastic for repairing the skin barrier, keeping skin hydrated, soft, and supple.
• Brightening: It effectively brightens the complexion and provides antioxidant protection.
• Ideal for Sensitive Skin: Unlike harsh actives, Malassezin is suitable for all skin types, especially those with sensitive or barrier-damaged skin.

Look for Malassezin in our latest range of serums and creams.

3. Magnesium Capsules: The Internal Glow Fix

Beauty sleep is real, and Magnesium is the key to unlocking it.

Stress and poor sleep are major contributors to aesthetic concerns like hair fall, pigmentation, and acne. By addressing the root cause with Magnesium capsules, you can:

• Improve Sleep Quality: It regulates melatonin to help you rest better [6].
• Reduce Stress: It calms the nerves, provides mental relaxation, and lowers stress levels.

When your stress is gone and you sleep well, your skin and hair naturally recover [7].

4. Plant-Based Adaptogens: Nature’s Stress Busters

In 2025, skincare is going holistic with Adaptogens. These are herbs that help your body resist and adapt to physical and mental stress. They are available in oral supplements and cream-based forms.

Top Adaptogens to Know:

• Ashwagandha (Indian Ginseng):
  • A prominent herb in Ayurveda found in India and the Middle East.
  • Restores normal bodily function, improves cognitive function, and enhances athletic performance [8,9].
  • Known to increase testosterone levels.
• Tulsi (Holy Basil):
  • A revered aromatic herb from the mint family.
  • Balances blood sugar and blood pressure while reducing body inflammation.
  • Acts as an immunity supporter and a remedy for cough and cold (often used in kadha).
• Ginseng:
  • A popular medicinal plant used for centuries in Asian medicine.
  • Famous for boosting energy levels and reducing stress.
• Licorice Root:
  • Contains anti-inflammatory and antioxidant effects.
  • Used in beauty products as well as traditional medicine for respiratory and digestive issues.

5. Phytoestrogens: Balancing Hormones Naturally

Hormonal balance is crucial for maintaining youthful skin. Phytoestrogens are plant-based compounds that mimic estrogen, helping to balance hormones and potentially ease menopause symptoms [10]. They also help reduce cancer risk [11].

Where to Find Them:

• Soy Products: Tofu, tempeh, soy milk, miso.
• Seeds & Nuts: Flaxseeds, sesame seeds, almonds.
• Legumes: Lentils, beans, chickpeas.
• Fruits & Veggies: Berries, apples, carrots, broccoli.
• Herbs: Red clover, hops, chaste berry.

6. DHEA: The Anti-Aging Hormone

DHEA (Dehydroepiandrosterone) is a natural steroid hormone produced by the adrenal glands. It acts as a precursor to male and female hormones like testosterone and estrogen.

The Skin Connection: When DHEA levels decrease, anti-aging signs like fine lines and wrinkles appear. Supplementing DHEA (available in creams or supplements) can:

• Improve skin thickness, firmness, and elasticity.
• Boost collagen production and hydration [12].
• Decrease the appearance of wrinkles [13].

7. Liquid IV: The Hydration Multiplier

Hydration is the foundation of healthy skin. Liquid IV is a trending hydration multiplier designed to hydrate you faster than water alone.

How It Works: It uses CTT (Cellular Transport Technology), a specific ratio of glucose, sodium, and potassium to deliver water and electrolytes directly into your cells [14].

Who Is It For? Unlike standard vitamin supplements which restore nutritional lag, Liquid IV is for acute dehydration. It is ideal for:

• Gym-goers or those working outdoors in the sun.
• Recovering from jet lag or hangovers.
• Anyone feeling exhausted or dehydrated.

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Ready to Upgrade Your Skincare Routine?

2025 is all about smarter, science-backed choices. Whether you are looking for the internal repair of NAD+, the gentle power of Malassezin, or the hormonal support of DHEA, we can help you create a personalized aesthetic plan.

Book a consultation with us today to discover which of these trending treatments is right for you!

References

1. Covarrubias, A. J., et al. (2021). “NAD+ metabolism and its roles in cellular processes during aging.” Nature Reviews Molecular Cell Biology.
2. Fang, E. F., et al. (2017). “NAD+ in Aging: Molecular Mechanisms and Translational Implications.” Trends in Molecular Medicine.
3. Poddar, S. K., et al. (2019). “Nicotinamide Mononucleotide: Exploration of Diverse Therapeutic Applications of a Potential Molecule.” Biomolecule.
4. Wana, B., et al. (2022). “Histopathological Changes Induced by Malassezin: A Novel Natural Microbiome Indole for Treatment of Facial Hyperpigmentation.” Journal of Drugs in Dermatology.
5. Maghfour, J., et al. (2022). “The Role of the Skin Microbiome in the Pathogenesis of Hyperpigmentation.” Dermatology and Therapy.
6. Arab, A., et al. (2023). “The Role of Magnesium in Sleep Health: a Systematic Review of Available Literature.” Biological Trace Element Research.
7. Pickering, G., et al. (2020). “Magnesium Status and Stress: The Vicious Circle Concept Revisited.” Nutrients.
8. Chandrasekhar, K., et al. (2012). “A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of ashwagandha root in reducing stress and anxiety in adults.” Indian Journal of Psychological Medicine.
9. Choudhary, D., et al. (2017). “Efficacy and Safety of Ashwagandha (Withania somnifera (L.) Dunal) Root Extract in Improving Memory and Cognitive Functions.” Journal of Dietary Supplements.
10. Chen, M. N., et al. (2015). “Efficacy of phytoestrogens for menopausal symptoms: a meta-analysis and systematic review.” Climacteric.
11. Theriault, R. L., et al. (2014). “The potential health effects of dietary phytoestrogens.” Cancer Prevention Research.
12. Shin, M. H., et al. (2005). “Modulation of collagen metabolism by the topical application of dehydroepiandrosterone to human skin.” Journal of Investigative Dermatology.
13. Labrie, F., et al. (2000). “Dehydroepiandrosterone (DHEA), DHEA sulfate, and aging: contribution of the DHEAge Study to a sociobiomedical issue.” Proceedings of the National Academy of Sciences.
14. Binder, H. J., et al. (2014). “Role of Colonic Short-Chain Fatty Acid Transport in Diarrhea.” Annual Review of Physiology (explaining the sodium-glucose mechanism).